Is the Risk for Prostate Cancer in Men and Dogs Similarly Affected by Aging?

Comparing the Age at Prostate Cancer Diagnosis in Humans and Dogs
Waters et al, J Natl Cancer Inst 1996; 88:1686

METHODS

686 pet dogs with spontaneous prostate cancer

Chronological age at diagnosis adjusted to physiologic age and expressed
in human age equivalents

Canine data compared to human prostate cancer incidence data prior to serum PSA screening (n=110 cases)

Algorithm Used to Convert the Chronologic Age of Pet Dogs to Physiologic Age (Patronek et al, J Gerontol 1997, 52A:B171)

Physiologic age (human year equivalents) =

{[(-0.0013 * X) + 0.0221]*C³}
+ {[( -0.0285* X) - 0.1071]*C²}
+ {[(0.2911 * X) + 4.9979]*C}
+ (-3.6437 * X) + 37.423

where X = breed-specific median age at death (years) and C = chronological age (years)